Which is a symptom commonly associated with macromineral toxicity?

Constipation is a symptom that can be commonly associated with macromineral toxicity, particularly when it comes to excessive intake of certain minerals like calcium. When intake of calcium or magnesium is significantly higher than the recommended levels, it can lead to changes in gut motility and function, often resulting in constipation. This effect is due to the way that high levels of these minerals can alter the balance of electrolytes and affect the muscle contractions of the intestines.

Other symptoms such as headaches, fatigue, and nausea can occur with various conditions or due to other causes and are not as specifically linked to macromineral toxicity as constipation is. Understanding the specific effects of macrominerals on the body helps clarify why constipation is the more definitive symptom in this context.