Which statement is true about lipoprotein composition?

The statement regarding lipoprotein composition that is true asserts that LDL contains more cholesterol than HDL or VLDL. This is accurate because low-density lipoprotein (LDL) is often referred to as "bad cholesterol." It is rich in cholesterol esters and is a primary carrier of cholesterol in the bloodstream. Its main role is to deliver cholesterol to cells, and it is considered atherogenic, meaning it can contribute to plaque buildup in arteries.

In comparison, high-density lipoprotein (HDL) is known as "good cholesterol" and has a higher proportion of protein relative to its lipid content. It is involved in reverse cholesterol transport, taking cholesterol from the tissues back to the liver. Very-low-density lipoprotein (VLDL) primarily carries triglycerides rather than cholesterol, making its composition lean more toward fat than the lipid makeup of LDL.

Understanding these distinctions is crucial for grasping the roles that different lipoproteins play in cardiovascular health, metabolism, and how they relate to diseases like atherosclerosis.